B Cell Receptor Signaling by Tomohiro Kurosaki

B Cell Receptor Signaling



B Cell Receptor Signaling pdf free

B Cell Receptor Signaling Tomohiro Kurosaki ebook
Publisher: Springer International Publishing
Format: pdf
ISBN: 9783319261317
Page: 231


Signalling through the B cell receptor (BCR) is central to the development and maintenance of B cells. B cell receptor signaling pathway - Homo sapiens (human), Help. This review updates on the recent findings surrounding B cell receptor signaling function in human systemic lupus erythematosus. Doi: 10.1053/j.seminhematol.2015.01.008 . Pre-B cell receptor signaling mediates selective response to IL-7 at the pro-B to pre-B cell transition via an ERK/MAP kinase-dependent pathway. Targeting the B-cell receptor signaling pathway in B lymphoid malignancies. The B cell antigen receptor (BCR) is composed of membrane immunoglobulin (mIg) molecules and associated Igα/Igβ (CD79a/CD79b) heterodimers (α/β). Basal B-cell receptor signaling in B lymphocytes: mechanisms of regulation and role in positive selection, differentiation, and peripheral survival. The B-cell receptor signaling pathway as a therapeutic target in CLL. Kinetics of B cell receptor signaling in human B cell subsets mapped by phosphospecific flow cytometry. B-cell receptor signaling in diffuse large B-cell lymphoma. The mIg subunits bind antigen, resulting in receptor aggregation, while the α/β subunits transduce signals to the cell interior. Self-enforcing feedback activation between BCL6 and pre-B cell receptor signaling defines a distinct subtype of acute lymphoblastic leukemia.





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